The WHO reports that 1 in 6 women suffer from iron deficiency anemia (IDA), among women of reproductive age (15-49). [1] Despite various iron supplements on the market, many solutions fail to address the core challenges of poor iron bioavailability, and the side effects associated with increased iron intake, such as the growth of enteric pathogens. [2] TCI837, TCI’s exclusive probiotic Lactiplantibacillus plantarum strain presents an innovation in iron supplementation, offering enhanced absorption without common drawbacks.
Synergistic Probiotic Iron Support
Developed using TCI bioresource mining technology, TCI837 is a probiotic isolated from raisins and specifically chosen for its unique properties in iron absorption. Unlike traditional probiotics or supplements, TCI837 does not compete with the host for iron. Instead, it works with the body by inducing mucin secretion in intestinal cells. [3] This mucin binds to iron, facilitating better absorption and reducing the likelihood of unabsorbed iron fostering pathogenic bacterial growth. [4,5]
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Holistic Health Benefits
- Enhanced Iron Bioavailability: TCI837 improves iron absorption by converting insoluble Fe3+ into the more easily absorbed Fe2+ form. In an internal human trial, women aged 20-55 with anemia or known to have low hemoglobin levels experienced a 94% increase in serum ferritin after just two weeks of supplementing with TCI837 and iron. *
- Comprehensive IDA Symptom Relief: TCI837 significantly improves red blood cell (RBC), hemoglobin (Hb), and hematocrit (Hct) levels. After four weeks of supplementation, participants experienced a significant increase in blood markers: red blood cell (RBC) count by 58%, hemoglobin levels increased by 53%, and hematocrit improved by 13%. * These improvements translate into better oxygen transport and reduced symptoms of anemia, such as fatigue and weakness.
- Promotes Gut Health: TCI837 not only enhances iron absorption but also helps maintain a healthy gut microbiome by inhibiting the growth of harmful bacteria, such as Enterobacteriaceae and Campylobacter. At the same time, it promotes the growth of beneficial short-chain fatty acid (SCFA) producing bacteria, which are essential for supporting gut barrier functions and overall health. *
TCI837 is an award-winning probiotic for iron supplementation, recognized with the Silver Award at the Seoul International Invention Fair for its novel approach to improving iron absorption. It represents a powerful and innovative solution for iron deficiency, particularly for women who are most vulnerable to IDA. In addition, TCI837 also supports gut health by inhibiting the growth of harmful pathogens and promoting beneficial bacteria, addressing common side effects seen with traditional iron supplements. Its proven efficacy, combined with its gut-friendly formulation, makes TCI837 a groundbreaking solution for businesses seeking to offer a superior, scientifically backed iron supplement.
* Data from TCI internal study
- World Health Organization. Prevalence of anaemia in women of reproductive age (aged 15-49) (%). World Health Organization. https://www.who.int/data/gho/data/indicators/indicator-details/GHO/prevalence-of-anaemia-in-women-of-reproductive-age-(-)
- Kortman, G. A., Boleij, A., Swinkels, D. W., & Tjalsma, H. (2012). Iron availability increases the pathogenic potential of Salmonella typhimurium and other enteric pathogens at the intestinal epithelial interface. PloS one, 7(1), e29968.
- Mack, D. R., Ahrné, S., Hyde, L., Wei, S., & Hollingsworth, M. A. (2003). Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro. Gut, 52(6), 827-833.
- Conrad, M. E., & Umbreit, J. N. (1993). A concise review: Iron absorption—The mucin‐mobilferrin‐integrin pathway. A competitive pathway for metal absorption. American journal of hematology, 42(1), 67-73.
- Conrad, M. E., Umbreit, J. N., & Moore, E. G. (1991). A role for mucin in the absorption of inorganic iron and other metal cations: a study in rats. Gastroenterology, 100(1), 129-136.
